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1 September 2001 Follicle Selection in Primates: “Many Are Called but Few Are Chosen”
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Abstract

During the follicular phase of humans and most nonhuman primates, a single preovulatory follicle usually matures each menstrual cycle. The observation that numerous preovulatory follicles may be stimulated to mature when exogenous gonadotropins are administered indicates that there must be a precise and highly reproducible mechanism by which only one of the many follicles capable of ovulating actually does so. The goal of this review is to summarize past and current research which indicates that follicle selection in primates is the result of an exquisitely sensitive interplay between gonadotropin secretion by the pituitary gland, steroid production by the ovary, and maturation-dependent alterations of the ovary's responsiveness to gonadotropins.

Anthony J. Zeleznik "Follicle Selection in Primates: “Many Are Called but Few Are Chosen”," Biology of Reproduction 65(3), 655-659, (1 September 2001). https://doi.org/10.1095/biolreprod65.3.655
Received: 13 October 2000; Accepted: 1 March 2001; Published: 1 September 2001
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