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29 January 2018 Meiosis: the chromosomal foundation of reproduction
Ewelina Bolcun-Filas, Mary Ann Handel
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Abstract

Meiosis is the chromosomal foundation of reproduction, with errors in this important process leading to aneuploidy and/or infertility. In this review celebrating the 50th anniversary of the founding of the Society for the Study of Reproduction, the important chromosomal structures and dynamics contributing to genomic integrity across generations are highlighted. Critical unsolved biological problems are identified, and the advances that will lead to their ultimate resolution are predicted.

Summary Sentence

The chromosomal dynamics that underlie meiosis, the defining event of gametogenesis, are reviewed, with a look forward to advances that are on the horizon.

© The Author(s) 2018. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com
Ewelina Bolcun-Filas and Mary Ann Handel "Meiosis: the chromosomal foundation of reproduction," Biology of Reproduction 99(1), 112-126, (29 January 2018). https://doi.org/10.1093/biolre/ioy021
Received: 25 November 2017; Accepted: 23 January 2018; Published: 29 January 2018
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15 PAGES

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