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22 February 2018 Hemochorial placentation: development, function, and adaptations
Michael J. Soares, Kaela M. Varberg, Khursheed Iqbal
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Abstract

Placentation is a reproductive adaptation that permits fetal growth and development within the protected confines of the female reproductive tract. Through this important role, the placenta also determines postnatal health and susceptibility to disease. The hemochorial placenta is a prominent feature in primate and rodent development. This manuscript provides an overview of the basics of hemochorial placental development and function, provides perspectives on major discoveries that have shaped placental research, and thoughts on strategies for future investigation.

Summary Sentence

The review presents basic concepts of hemochorial placentation, discusses significant contributions to the field, and highlights experimental approaches for future investigation.

© The Author(s) 2018. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com
Michael J. Soares, Kaela M. Varberg, and Khursheed Iqbal "Hemochorial placentation: development, function, and adaptations," Biology of Reproduction 99(1), 196-211, (22 February 2018). https://doi.org/10.1093/biolre/ioy049
Received: 5 January 2018; Accepted: 21 February 2018; Published: 22 February 2018
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