Recent studies from my laboratory, showing the chemical castration (demasculinization) and feminization of amphibians by low but ecologically relevant concentrations of atrazine in the laboratory and in the wild, prompted a critical response from atrazine's manufacturer, Syngenta Crop Protection, and Syngenta-funded scientists. A careful analysis of the published data funded by Syngenta, and of several studies submitted to the US Environmental Protection Agency (EPA) by the Syngenta-funded panel for data evaluation, indicates that the data presented in these studies are not in disagreement with my laboratory's peer-reviewed, published data. Further, the published and unpublished data presented to the EPA by the Syngenta-funded panel (and touted in the popular press) suffer from contaminated laboratory controls; high mortality; inappropriate measurements of hormone levels in stressed, sexually immature animals during nonreproductive seasons; and contaminated reference sites. The confounding factors in the industry-funded studies severely limit any conclusions about the adverse effects of atrazine on amphibians and prevent meaningful comparisons with my laboratory's published data.
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Vol. 54 • No. 12