Smit, M. N., Zamora, V., Young, M. G., Campbell, N., Uttaro, B. and Beltranena, E. 2015. Empiric narrowing of the net energy value of reduced-oil corn distillers' dried grain with solubles for growing-finishing pigs. Can. J. Anim. Sci. 95: 225-241. This study attempted to empirically narrow down the net energy (NE) value of reduced-oil corn distillers' dried grains and solubles (RO-cDDGS) by evaluating the response in pig growth performance, live backfat and loin depth, carcass traits, and primal pork cuts tissue composition to feeding diets formulated increasing the assumed NE value of RO-cDDGS, expecting a brisk change in slope of the response at the point at which the NE value of RO-cDDGS would be identified. In total, 1056 cross-bred pigs (31.7 kg) housed in 48 pens by gender were fed dietary regimens including 30% RO-cDDGS (6.7% ether extract) with assumed NE values of 1.7, 1.85, 2.0, 2.15, 2.3, or 2.45 Mcal kg^-1 over five growth periods (Grower 1: days 0-21, Grower 2: days 22-42, Grower 3: days 43-63, Finisher 1: days 64-76, Finisher 2: day 77 to market weight). Pig body weights were measured and feed disappearance (ADFI) was calculated by pen on days 0, 21, 42, 63, 76 and weekly thereafter until target slaughter weight (120 kg). For the entire trial (days 0-76), increasing the assumed NE value of RO-cDDGS linearly increased (P<0.01) ADFI and total lysine intake, did not affect NE intake and daily weight gain (ADG), quadratically decreased (P<0.05) feed efficiency, linearly decreased (P<0.05) live backfat depth and backfat:loin depth ratio, and did not affect carcass characteristics or pork primal cut tissue composition. Segmented regression only identified a change in slope for carcass ADG and lean ADG at 1.85 Mcal kg^-1. These results indicate that the experimental approach taken was not reliable in narrowing down the NE value of RO-cDDGS because the decrease in dietary NE was too small (0.03 Mcal kg^-1 d), which limited the change in dietary Lys:NE ratio with increasing assumed NE value of RO-cDDGS. The approach resulted in progressive, but small changes in slope rather than a clearly identifiable point where one could conclude that the incremental dietary energy contribution from RO-cDDGS changed the response in a given variable.