The comparative parasitology of endemic, primarily fossorial squamate reptiles of xeric habitats in Florida, U.S.A., is described, largely based on live-trapping studies in Ocala National Forest, Marion County, Florida, from 1992 through 1998. Nineteen new host records (*) are reported, and a new species of Isospora is described. Neoseps reynoldsi (Scincidae) is host to Eimeria egregia*, Isospora neosepsorum n. sp.*, probably 2 species of Hartmannella, Parapharyngodon ocalaensis, and Eutrombicula* sp.; Eumeces egregius onocrepis (Scincidae) is parasitized by Proteromonas lacertaeviridis*, Monocercomonas colubrorum*, Retortamonas saurarum, E. egregia, Hartmannella spp.*, P. ocalaensis*, and Eutrombicula* sp.; Tantilla relicta relicta (Colubridae) is host to P. lacertaeviridis*, M. colubrorum*, R. saurarum*, Hartmannella spp., Eimeria pleistocenensis, E. amphorae, Eimeria sp., Isospora wilsoni, Caryospora tantillae, C. relictae, Kalicephalus inermis*, and P. ocalaensis*; Sceloporus woodi (Phrynosomatidae) is parasitized by M. colubrorum*, P. lacertaeviridis, R. saurarum*, a possible Hexamastix species, and Eutrombicula* sp.; Rhineura floridana (Amphisbaenidae) is the host of Paradollfusnema telfordi. Other saurian species examined, not endemic to the sandhills community, were Cnemidophorus sexlineatus (Teiidae), host to P. lacertaeviridis, M. colubrorum, R. saurarum, larval Physaloptera sp., and Eutrombicula* sp., and Scincella lateralis (Scincidae), parasitized by Eimeria scincellae, Hartmannella spp.*, and a cestode, Bitegmen sp.*