Echinococcus multilocularis can cause serious disease and even death in humans. Despite its human health implications, nearly 20 years have elapsed since the last surveys for E. multilocularis have been conducted in the United States. Between April 2009 and December 2012, 302 coyotes (Canis latrans), gray foxes (Urocyon cinereoargenteus), and red foxes (Vulpes vulpes) from Michigan were examined for E. multilocularis. The cestode was identified in 1 coyote (0.4%, n  =  223 coyotes) from the southwest portion of the state, representing the first report of E. multilocularis in this species in Michigan. Prevalence was lower than expected based on previous results in red foxes and coyotes in Michigan and nearby states.