Based on our ongoing studies of the bryophyte flora of Ecuador we report fifteen liverwort species new to the country: Cheilolejeunea ornata, Drepanolejeunea integribracteata, Frullania lindenbergii, Kymatocalyx rhizomatica, Lejeunea corynantha, Leptoscyphus cleefii, L. spectabilis, Plagiochila bicuspidata, P. cuatrecasii, P. priceana, Radula xalapensis, Symphyogyna trivittata, Syzygiella burghardtii, S. contigua and S. trigonifolia. Notes are provided on the distribution, habitat and taxonomic differentiation of the species. Plagiochila priceana and Syzygiella burghardtii are new to science and Plagiochila inouei is a new synonym of P. bicuspidata. Keys are presented to northern Andean species of Leptoscyphus and Syzygiella.