Theoretical models of the accumulation of Dobzhansky-Muller incompatibilities (DMIs) are studied, and in particular, the framework introduced by Orr (1995) and a verbal model introduced by Kondrashov et al. (2002). These models embody very different assumptions about the relationship between the substitution process underlying evolutionary divergence and the formation of incompatibilities. These differences have implications for our ability to make inferences about the divergence from patterns in the relevant data. With this in mind, the models are investigated for their ability to account for three patterns evident in this data: (1) the asymmetrical nature of incompatibilities under reciprocal introgression; (2) the finding that multiple concurrent introgressions may be necessary for an incompatibility to form; and (3) the finding that the probability of obtaining an incompatibility by introgressing a single amino acid remains roughly constant over a wide range of genetic distances. None of the models available in the literature can account for all of the empirical patterns. However, modified versions of the models can do so. Ways of discriminating between the different models are then discussed.
You have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither BioOne nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.
Translations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the BioOne website.
Vol. 58 • No. 6