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1 February 2006 Linkage Disequilibria and Haplotype Structure of Four SNPs of the Interleukin 1 Gene Cluster in Seven Asian Indian Populations
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Abstract

Variation at four single nucleotide polymorphism (SNP) sites of the interleukin 1 (IL1) gene cluster was investigated among 280 unrelated individuals, representing 7 caste groups from the state of Karnataka, India, and one European American community of Boston, Massachusetts. Allele and haplotype frequencies, strength of linkage disequilibrium, and signatures of recombination varied considerably among populations. Variable community sizes and traditions of consanguinity may account for the observed variation.

Srilakshmi M. Raj, Ranajit Chakraborty, Ning Wang, and Diddahally R. Govindaraju "Linkage Disequilibria and Haplotype Structure of Four SNPs of the Interleukin 1 Gene Cluster in Seven Asian Indian Populations," Human Biology 78(1), 109-119, (1 February 2006). https://doi.org/10.1353/hub.2006.0026
Received: 11 April 2005; Accepted: 1 August 2005; Published: 1 February 2006
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