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1 February 2006 Haptoglobin Gene Promoter Polymorphism and Haplotypes Are Unique in Different Populations
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Abstract

We investigated the distribution of haptoglobin (HP) alleles and haplotypes among Africans (Ghanaians), Europeans (from South Africa), and Chinese. HP*1F was present only in Africans and Europeans, whereas HP*del was unique to Chinese. Six base substitutions at the promoter region were population specific. Only 3 out of 18 haplotypes were shared among the populations. A probable application of HP in human population genetics appears legitimate.

Kwesi Teye, Mikiko Soejima, Isaac K. E. Quaye, Hao Pang, Makoto Tsuneoka, Yoshiro Koda, and Hiroshi Kimura "Haptoglobin Gene Promoter Polymorphism and Haplotypes Are Unique in Different Populations," Human Biology 78(1), 121-126, (1 February 2006). https://doi.org/10.1353/hub.2006.0029
Received: 6 August 2004; Accepted: 1 June 2005; Published: 1 February 2006
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