Monoterpenoids and low pressure have each been demonstrated to cause mortality of stored-product insect pests. The current report investigated the prospects of integrating the two methods in the management of diapausing and nondiapausing larvae of Plodia interpunctella (Hübner). In a separate experiment, the larvae were exposed to 35.5 mmHg in Erlenmeyer flasks at 19 and 28°C for times ranging from 30 min to 96 h. Another set of experiments was conducted to investigate the toxicity of exposing P. interpunctella larvae to monoterpenoids including E-anethole, estragole, S-carvone, linalool, L-fenchone, geraniol, γ-terpinene, and DL-camphor alone or in combination with low pressure (50 mmHg). Lethal times (LT) determined by subjecting time-mortality data to probit analyses were shortened to half when both diapausing and nondiapausing larvae were exposed to low pressure at 28°C compared with 19°C. Exposure of diapausing larvae to a monoterpenoid alone, with the exception of DL-camphor and estragole, at a concentration of 66.7 µl/1L of volume required >30 h to generate 99% mortality at 19.0 ± 0.8^°C. However, the LT₉₉ values for diapausing and nondiapausing larvae exposed to combinations of DL-camphor or estragole and low pressure were considerably shortened. Combinations involving the rest of the monoterpenoids investigated and low pressure did not generate LT₉₉ that were shorter than those of the control, which was low pressure only. These results suggest that integrating low pressure with DL-camphor or estragole could be a new method for the control of diapausing larvae of P. interpunctella at cooler temperatures.