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1 March 2014 Evaluation of Intramuscular Alfaxalone in Three Australian Frog Species (Litoria caerulea, Litoria aurea, Litoria booroolongensis)
Izidora Sladakovic, Robert S. Johnson, Larry Vogelnest
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Abstract

The effects of intramuscular (IM) alfaxalone were evaluated in three species of Australian frogs: Australian green tree frogs, (Litoria caerulea); green and golden bell frogs (Litoria aurea); and booroolong frogs (Litoria booroolongensis). Heart rate, respiration rate, responses, reflexes, spontaneous movement, time to effect, and duration of effect were measured. Other observations, including change in color and pupil size, were also noted. Alfaxalone administered IM at 30 mg/kg in Australian green tree frogs and 20 mg/kg in green and golden bell frogs achieved sedation and caused bradypnea. In booroolong frogs, a light plane of anesthesia and bradypnea occurred at 20 mg/kg IM. Apnea was not observed in any of the frogs, and there was no statistically significant bradycardia. No mortalities or adverse effects were noted.

Izidora Sladakovic, Robert S. Johnson, and Larry Vogelnest "Evaluation of Intramuscular Alfaxalone in Three Australian Frog Species (Litoria caerulea, Litoria aurea, Litoria booroolongensis)," Journal of Herpetological Medicine and Surgery 24(1), 36-42, (1 March 2014). https://doi.org/10.5818/1529-9651-24.1.36
Published: 1 March 2014
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KEYWORDS
alfaxalone
Anesthesia
Australian green tree frog
booroolong frog
green and golden bell frog
Litoria aurea
Litoria booroolongensis
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