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30 May 2022 Vascular Tumors in Two Argentine Horned Frogs (Ceratophrys ornata)
Mitsuhiro Ikeda, Hirotaka Kondo, Yuki Iwata, Iori Koizumi, Naoto Tsunesumi, Hisashi Shibuya
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Abstract

Two vascular tumors in two Argentine horned frogs (Ceratophrys ornata) are described. Case 1 involved a 7-yr-1-month-old Argentine horned frog that had a splenic mass with a sanguineous coelomic effusion. Histologically, the splenic parenchyma was effaced by a poorly demarcated, invasive mass consisting of spindle cells with marked nuclear atypia forming irregular blood vessel channels containing blood. Case 2 involved a pedunculated facial mass located at the upper right lip of an over-8-month-old Argentine horned frog. Histologically, the well-demarcated, poorly cellular mass consisted of sparse proliferation of spindle cells forming irregular slits with prominent edema. Immunohistochemically, the neoplastic cells of both cases were positive for anti-CD31 antibody. The diagnoses were hemangiosarcoma in Case 1 and lymphangioma in Case 2. To the best of the authors' knowledge, this is the first description of neoplastic diseases in captive Argentine horned frogs.

Mitsuhiro Ikeda, Hirotaka Kondo, Yuki Iwata, Iori Koizumi, Naoto Tsunesumi, and Hisashi Shibuya "Vascular Tumors in Two Argentine Horned Frogs (Ceratophrys ornata)," Journal of Herpetological Medicine and Surgery 32(2), 119-122, (30 May 2022). https://doi.org/10.5818/JHMS-D-21-00034
Published: 30 May 2022
JOURNAL ARTICLE
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KEYWORDS
Argentine horned frog
Ceratophrys ornata
hemangiosarcoma
lymphangioma
neoplasia
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