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1 October 2008 Outcome of ICSI with Morphologically Selected Spermatozoa
Yasushi Odawara, Takeshi Hosaka, Noriko Yoshii, Tomoko Kudo, Akane Abe, Satoshi Akimoto, Nobuyoshi Takeda
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Abstract

In ICSI, sperm is selected based on its motility and shape under 200–400× magnification. However, sperm morphology, especially the existence of vacuoles, may relate to sperm nuclear DNA fragmentation. Bartoov et al. reported the application of sperm selection under high (1,000–6,000×) magnification, which they referred to as IMSI (intracytoplasmic morphologically-selected sperm injection). In our initial trials, the fertilization, blastocyst development, pregnancy and miscarriage rates of 115 single blastocyst transfer cycles with IMSI or ICSI were 84.0% vs. 75.5%, 47.5% vs. 43.7%, 50.0% vs. 47.4% and 10.0% vs. 11.0%, respectively. Further studies are required to establish the systems and clarify the indications for IMSI.

Yasushi Odawara, Takeshi Hosaka, Noriko Yoshii, Tomoko Kudo, Akane Abe, Satoshi Akimoto, and Nobuyoshi Takeda "Outcome of ICSI with Morphologically Selected Spermatozoa," Journal of Mammalian Ova Research 25(4), 254-258, (1 October 2008). https://doi.org/10.1274/0916-7625-25.4.254
Published: 1 October 2008
JOURNAL ARTICLE
5 PAGES

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KEYWORDS
ICSI
IMSI
Male infertility
Morphologically sellected sperm injection
Oligozoospermia
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