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1 October 2015 Angiogenesis and Hormonal Regulation on Uterine Receptivity for Blastocyst Implantation
Hiromichi Matsumoto, Emiko Fukui, Midori Yoshizawa
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Abstract

Synchronization of embryonic development and differentiation of specific uterine cell types to a receptive state is essential for a successful pregnancy. The period of uterine receptivity for implantation is limited. Increased vascular permeability and angiogenesis are hallmarks of the implantation process. Although implantation involves the interaction of numerous signaling molecules, the hierarchical mechanisms that coordinate the embryo—uterine dialog remain poorly understood. This review highlights our knowledge about angiogenesis, uterine receptivity, and hormonal regulation for blastocyst implantation in the mouse. A better understanding of uterine biology during the peri-implantation period would facilitate the further development of reproductive technology.

©2015 Japan Society for Ova Research
Hiromichi Matsumoto, Emiko Fukui, and Midori Yoshizawa "Angiogenesis and Hormonal Regulation on Uterine Receptivity for Blastocyst Implantation," Journal of Mammalian Ova Research 32(3), 79-85, (1 October 2015). https://doi.org/10.1274/jmor.32.79
Received: 7 May 2015; Accepted: 1 June 2015; Published: 1 October 2015
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7 PAGES

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KEYWORDS
angiogenesis
decidualization
implantation
steroid hormones
uterus
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