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1 November 2010 Antibody Response Against Anopheles albimanus (Diptera: Culicidae) Salivary Protein as a Measure of Mosquito Bite Exposure in Haiti
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Abstract

Antibodies against arthropod saliva have shown to be a good marker of bite exposure. Because Anopheles albimanus Wiedemann (Diptera: Culicidae) is the principal malaria vector in Haiti, we evaluated the immune response against salivary gland extract (SGE) of this species in malaria-positive and malaria-negative subjects from this country. The results showed that the level of anti-SGE immunoglobulin (Ig)G antibodies was higher in patients with clinical malaria than those in malaria uninfected people living in the same region. In addition, a significant positive correlation between the level of anti-An. albimanus IgG and IgM antibody levels was observed. These results suggest that antibodies against An. albimanus saliva, especially IgG, are useful markers of mosquito bite exposure in Haiti.

© 2010 Entomological Society of America
Berlin L. Londono-Renteria, Thomas P. Eisele, Joseph Keating, Mark A. James, and Dawn M. Wesson "Antibody Response Against Anopheles albimanus (Diptera: Culicidae) Salivary Protein as a Measure of Mosquito Bite Exposure in Haiti," Journal of Medical Entomology 47(6), (1 November 2010). https://doi.org/10.1603/ME09240
Received: 29 September 2009; Accepted: 1 August 2010; Published: 1 November 2010
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