Translator Disclaimer
9 June 2020 Susceptibility to Pyrethroids and the First Report of L1014F kdr Mutation in Culex quinquefasciatus (Diptera: Culicidae) in Colombia
Ronald Maestre-Serrano, Juan Lara-Cobos, Doris Gomez-Camargo, Gustavo Ponce-Garcia, Paula Pareja-Loaiza, Adriana E. Flores
Author Affiliations +
Abstract

The use of insecticides for the control of Aedes aegypti (L.) (Diptera: Culicidae) in Colombia has indirectly influenced the susceptibility status of Culex quinquefasciatus Say populations. We evaluated pyrethroid susceptibility in two populations of Cx. quinquefasciatus in the Atlantico Department of Colombia and its possible resistance mechanism (kdr mutation). Bottle bioassays were performed for permethrin, deltamethrin, and λ-cyhalothrin in female mosquitoes of Cx. quinquefasciatus.The resistance ratios (RRs) for KC50 and LC50 for each insecticide in the field populations examined were determined, using the Cartagena strain as the susceptible control.The L1014F kdr mutation was identified in the para gene of the voltage-gated sodium channel (vgsc), along with its allelic and genotypic frequency. Low knockdown resistance (RRKC50) to deltamethrin was found in Puerto Colombia and Soledad populations as well as low resistance to λ-cyalothrin in this latter population. Moderate knockdown resistance to permethrin was found in both populations. At 24 h post-exposure on the other hand, there was low resistance (RRLC50) to permethrin in Puerto Colombia and moderate resistance in Soledad. Moderate resistance to deltamethrin was found in Puerto Colombia and low resistance in Soledad. Low resistance to λ-cyhalothrin was seen in Puerto Colombia and moderate resistance in Soledad. Variability was found in the susceptibility to the pyrethroids in the populations of Cx. quinquefasciatus evaluated, and the L1014F kdr mutation is reported for the first time as a possible pyrethroid resistance mechanism in this species in Colombia.

© The Author(s) 2020. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Ronald Maestre-Serrano, Juan Lara-Cobos, Doris Gomez-Camargo, Gustavo Ponce-Garcia, Paula Pareja-Loaiza, and Adriana E. Flores "Susceptibility to Pyrethroids and the First Report of L1014F kdr Mutation in Culex quinquefasciatus (Diptera: Culicidae) in Colombia," Journal of Medical Entomology 57(6), 1830-1834, (9 June 2020). https://doi.org/10.1093/jme/tjaa098
Received: 17 March 2020; Accepted: 28 April 2020; Published: 9 June 2020
JOURNAL ARTICLE
5 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

Share
SHARE
KEYWORDS
Culex quinquefasciatus
insecticide resistance
kdr mutation
pyrethroid
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top