Translator Disclaimer
6 February 2019 Calodium hepaticum (Trichuroidea: Capillariidae) Infection in Akodon azarae: First Description of Histopathological Lesions in Sigmodontinae
M. C. Fantozzi, A. Sanchez, A. L. Scartascini Ciorciari, F. E. Peña, A. Canal, P. M. Beldomenico
Author Affiliations +
Abstract

Calodium hepaticum (Trichinellida: Capillaridae) is a parasitic nematode of mammals distributed worldwide. Although this parasite can infect the liver of a wide diversity of mammals (including humans), it is mostly associated with Muroidea hosts. Sigmodontinae rodents were recently recognized as important hosts of this parasite in Argentina, but the impact of this parasitism on these hosts has not been established. Here we report results of histopathological analyses of 40 livers of Akodon azarae infected with C. hepaticum. Lesions were classified into 4 categories: level 0, absence of lesions; level 1, with focal granulomatous hepatitis; level 2, presence of multifocal granulomatous hepatitis, fibrosis and focal necrosis with neutrophils, and level 3, absence of intact adult parasites, diffuse distribution, necrosis, and fibrosis. Most samples presented lesions of level 2 (55%), but all categories of lesions were found. This is the first study to describe the lesions caused by C. hepaticum in the liver of Sigmodontinae rodents, and the results suggest that infection by this parasite is costly to A. azarae populations.

© American Society of Parasitologists 2019
M. C. Fantozzi, A. Sanchez, A. L. Scartascini Ciorciari, F. E. Peña, A. Canal, and P. M. Beldomenico "Calodium hepaticum (Trichuroidea: Capillariidae) Infection in Akodon azarae: First Description of Histopathological Lesions in Sigmodontinae," Journal of Parasitology 105(1), 75-78, (6 February 2019). https://doi.org/10.1645/18-127
Published: 6 February 2019
JOURNAL ARTICLE
4 PAGES


Share
SHARE
KEYWORDS
Akodon azarae
Argentina
Calodium hepaticum
disease ecology
hepatic fibrosis
hepatitis
Histopathological Analyses
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top