Although Clonorchis sinensis is a parasite that still infects many people in East Asia, its genetics remain largely unknown. We conducted ancient DNA analysis of C. sinensis eggs obtained from a Joseon period mummy newly discovered in South Korea. Clonorchis sinensis DNA was amplified for internal transcribed spacer 1, cytochrome c oxidase subunit 1, and NADH dehydrogenase subunit 2 and 5 genes. The results of BLAST/NCBI showed that the consensus sequences were 98.24 to 100% identical to the modern and ancient C. sinensis sequences reported from Korea, China, Japan, and other Asian countries. Our report helps to fill in the genetic profile of ancient C. sinensis strains that infected East Asian people hundreds of years ago.
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15 February 2022
Genetic Analysis of Ancient Clonorchis sinensis Eggs Attained from Goryeong Mummy of Joseon Dynasty Period
Chang Seok Oh,
Min Seo,
Hye Jin Lee,
Myeung Ju Kim,
Do-Seon Lim,
Dong Hoon Shin
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Journal of Parasitology
Vol. 108 • No. 1
February 2022
Vol. 108 • No. 1
February 2022
ancient DNA
Clonorchis sinensis
Goryeong
Joseon period
Korea
mummy