Observations on the Exoerythrocytic Stages of Different Isolates of Plasmodium cynomolgi in Hepatocytes of New World Aotus and Saimiri Monkeys

JoAnn S. Sullivan; Ann Stewart; Amy Bounngaseng; James J. Sullivan; Douglas Nace; Allison Williams; G. Gale Galland; Tyrone Williams; Fleetwood Henry; William E. Collins§

doi:10.1645/GE-3520RN.1

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JoAnn S. Sullivan,¹ Ann Stewart,^1,* Amy Bounngaseng,^1,** James J. Sullivan,¹ Douglas Nace,¹ Allison Williams,¹ G. Gale Galland,¹ Tyrone Williams,^1,** Fleetwood Henry,^1,*** William E. Collins§¹

¹Division of Parasitic Diseases and Scientific Resources Program, National Center for Infectious Dise

^** Department of Immunology, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910;
^**† Atlanta Research and Education Foundation, Atlanta, Georgia 30033;
^***‡ Division of Pathology, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910;

Abstract

Sporozoites of 3 isolates of Plasmodium cynomolgi dissected from the salivary glands of Anopheles dirus and Anopheles quadrimaculatus were injected intravenously into 9 New World monkeys. Liver stage parasites were demonstrated in all 9 animals; 7 of these animals also produced blood stages after prepatent periods of 9 to 23 days.

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JoAnn S. Sullivan, Ann Stewart, Amy Bounngaseng, James J. Sullivan, Douglas Nace, Allison Williams, G. Gale Galland, Tyrone Williams, Fleetwood Henry, and William E. Collins§ "Observations on the Exoerythrocytic Stages of Different Isolates of Plasmodium cynomolgi in Hepatocytes of New World Aotus and Saimiri Monkeys," Journal of Parasitology 92(1), 202-205, (1 February 2006). https://doi.org/10.1645/GE-3520RN.1

Published: 1 February 2006

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