Water footprint of production can be used to identify pressure on national or regional water resources generated by production activities. Water stress is defined as the ratio of water use (the difference between a regional water footprint of production and a green water footprint) to renewable water resources available in a country or region. Water stress can be used to identify pressure on national or regional water resources generated by production activities. This paper estimates the water footprint of production and the water stress in China during the years 1985–2009. The result shows that China's water footprint of production increased from 781.58 × 10⁹ m³ in 1985 to 1109.76 × 10⁹ m³ in 2009. Mega-cities and regions with less agriculture production due to local climatic conditions (Tibet and Qinghai) had lower water footprint of production, while the provinces (Henan, Shandong) with higher agriculture production had higher footprint. Provinces with severe water stress increased from 6 in 1985 to 9 in 2009. High to severe water stress exists mainly in mega-cities and agricultural areas located in the downstream areas of the Yellow River and the Yangtze River in North and Central China. The outlook for water resources pressure in China is not optimistic, with areas of stress expanding from northern to southern of China.