Jiangyin was the earliest to conduct Non-development zone planning and has attracted the attention of people all over China because it is regarded as the Chinese version of Smart Growth. The planning process is as follows. Based on SPOT and TM satellite remote sensing images develop a regional land use map with high precision using artificial interpretation methods. Then, according to the relationship between anti-development suitability and disasters, agriculture, ecology, built-up area distribution and other geographical factors, generate a comprehensive evaluation chart of anti-development suitability using GIS analysis, such as buffer analysis and overlay analysis. Later, with a regional land use map and anti-development suitability evaluation chart, using the principle of ecological security network and learning from the management experience of nature reserves, draw the scope of Non-development zone and core area. Last, put forward a series of protective measures for the above Non-development zone, that is only allowed to develop agriculture and tourism, strictly restricted industrial projects and urban real estate activities, and all existing industrial factories must be moved to planned industrial parks. This is good practice whereby local governments keep land resources for future generations and more advanced than an urban expansion strategy. This method is very useful for promoting land use layout optimization in Southern Jiangsu Developed Areas.