The Patagonian red octopus Enteroctopus megalocyathus (Gould, 1852) is one of the most important octopus fishing resources in Patagonian Atlantic and Patagonian Pacific coasts, but there is no information available regarding the biological aspects of the species in intertidal environments. In this work, maturity condition of E. megalocyathus and composition of the capture obtained by a small-scale fishery on intertidal rocky shores in the north of San Jorge Gulf (Patagonian Atlantic coast) were investigated, together with the fishing capacity of the fishermen who operate in the area. Throughout each of the three fishing seasons analyzed, a progressive increase in sexual maturity stages was observed for both sexes. Mature-spawning and spent females were not registered in the catches, whereas mature males constituted only 7.5% of the total catches. Females were heavier than males at a given mantle length. Weight composition of catches revealed the presence of middle-weight animals in all fishing months and an increase in mean weights along the fishing season. Toward the end of the fishing period, the proportion of mature males increased and females outnumbered males. At that time, lighter and immature octopuses recruited to fishing areas, mean weight of the catches decreased, and most fishermen stopped fishing. The mean individual catch was 18.1 kg/fisherman-day, but it was highly variable. Results suggest that females reach maturity, become able to copulate, and spawn in the following months away from fishing grounds, whereas the reproductive stock remains little affected.