One new species of ailurid and two new genera and species of oligobunine mustelids are recognized from the early Hemingfordian (He1) Miller Local Fauna, Dixie/Levy County, Florida (U.S.A.). The ailurid is congeneric with the European early Miocene Amphictis but is smaller than the Old World species. One new oligobunine is a small hypercarnivore with a reduced metaconid and talonid on m1 and is related to Promartes and Oligobunis. The second is a small hypocarnivore with an enlarged metaconid on m1 and a relatively large m2 and is is related to Brachypsalis. Four other mustelids new to the Miller Local Fauna are the oligobunines cf. Brachypsalis sp. and cf. Oligobunis sp. and the leptarctines Craterogale cf. simus and Leptarctus ancipidens. These small carnivorans most closely resemble those of the early Hemingfordian Runningwater Formation of the better known northern Great Plains faunas and add further support that the Miller Local Fauna is older than the late early or early late Hemingfordian Thomas Farm.