OBSERVATIONS ON BLUETONGUE AND EPIZOOTIC HEMORRHAGIC DISEASE VIRUSES IN WHITE-TAILED DEER: (1) DISTRIBUTION OF VIRUS IN THE BLOOD (2) CROSS-CHALLENGE1

GERALD L. HOFF

doi:10.7589/0090-3558-10.1.25

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1 January 1974 OBSERVATIONS ON BLUETONGUE AND EPIZOOTIC HEMORRHAGIC DISEASE VIRUSES IN WHITE-TAILED DEER: (1) DISTRIBUTION OF VIRUS IN THE BLOOD (2) CROSS-CHALLENGE

GERALD L. HOFF

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J. of Wildlife Diseases, 10(1):25-31 (1974). https://doi.org/10.7589/0090-3558-10.1.25

Abstract

The viruses of bluetongue and epizootic hemorrhagic disease produced cell associated viremias in white-tailed deer (Odocoileus Virginianus). Highest virus titers were associated with the erythrocytes. The titers of virus in the erythrocyte fraction of blood were consistently higher than those in the leukocyte fraction, although virus persisted in both fractions for approximately the same length of time. All detectable viremia disappeared within 6 to 8 days following the development of virus-specific neutralizing antibodies. These antibodies failed to confer protection against challenge with virulent heterologous virus, although the time of death was delayed 3 to 11 days in comparison with control deer.

HOFF and TRAINER: OBSERVATIONS ON BLUETONGUE AND EPIZOOTIC HEMORRHAGIC DISEASE VIRUSES IN WHITE-TAILED DEER: (1) DISTRIBUTION OF VIRUS IN THE BLOOD (2) CROSS-CHALLENGE1

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GERALD L. HOFF "OBSERVATIONS ON BLUETONGUE AND EPIZOOTIC HEMORRHAGIC DISEASE VIRUSES IN WHITE-TAILED DEER: (1) DISTRIBUTION OF VIRUS IN THE BLOOD (2) CROSS-CHALLENGE," Journal of Wildlife Diseases 10(1), 25-31, (1 January 1974). https://doi.org/10.7589/0090-3558-10.1.25

Received: 16 July 1973; Published: 1 January 1974

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