California quail (Lophortyx californicus) from several locations in Oregon were examined seasonally between fall 1975 and summer 1978 for avian pox. Pox lesions were present on 66 of 256 (26%) birds from the E.E. Wilson Wildlife Area. None of the remaining 41 birds from other areas was infected. Rates of infection of males and females were equal; juveniles had a slightly, but not significantly, higher prevalence of pox than did adults.