Fatal cases of herpesvirus infection in a quokka (Setonix brachyurus), eight grey dorcopsis wallabies (Dorcopsis muelleri luctuosa) in two separate outbreaks, as well as presumptive fatal herpesvirus infection in a western grey kangaroo (Macropus fuliginosus) are described. All were captive animals and deaths were preceded by a period of stress. Lesions occurred most often in alimentary tract epithelium, respiratory tract, skin, genital epithelium, conjunctivae, liver and adrenal cortex. Herpesviruses were recovered from the quokka and a grey dorcopsis wallaby from each outbreak. The implications, particularly concerning certain apparently susceptible species, for those responsible for the health of macropod collections are discussed.