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1 October 1988 Use of Xylazine Sedation with Yohimbine Antagonism in Captive Gray Wolves
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Abstract

Captive gray wolves (Canis lupus) were given 2.2 mg/kg xylazine hydrochloride intramuscularly resulting in profound sedation in 9.1 ± 0.6 min (mean ± SE). Heart rate was 42.0 ±1.0 beats per minute and respiratory rate was 20.1 ± 1.6 respirations per minute during sedation. A variety of manipulations could be performed on sedated animals in relative safety. Thirty min after xylazine administration, the animals were given either 0.15 mg/kg yohimbine hydrochloride or 5% dextrose solution intravenously causing recovery in 5.3 ± 1.0 and 97.1 ± 14.0 min, respectively (P < 0.001).

Kreeger, Seal, Callahan, and Beckel: Use of Xylazine Sedation with Yohimbine Antagonism in Captive Gray Wolves
Terry J. Kreeger, Ulysses S. Seal, Margaret Callahan, and Mark Beckel "Use of Xylazine Sedation with Yohimbine Antagonism in Captive Gray Wolves," Journal of Wildlife Diseases 24(4), 689-690, (1 October 1988). https://doi.org/10.7589/0090-3558-24.4.689
Received: 26 January 1988; Published: 1 October 1988
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