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1 April 1991 HEPATIC LESIONS IN WOODCHUCKS (MARMOTA MONAX) SERONEGATIVE FOR WOODCHUCK HEPATITIS VIRUS
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Abstract

Livers from 128 captive woodchucks (Marmota monax) that were negative for serological markers of woodchuck hepatitis virus (WHV) were examined grossly and histologically. Livers from 19 additional seronegative woodchucks were examined only grossly. The most common finding (61% of histological specimens) was mononuclear cells in portal areas. Moderate to severe portal infiltrates in association with similar scattered mononuclear cell aggregates and extramedullar hematopoiesis, were present in woodchucks that had extrahepatic inflammatory lesions. We concluded that these changes represent a response to a variety of chronic infections and are not specific for WHV infection. Other findings included parasitic granulomas, focal and diffuse lipidosis, bile duct proliferation, lesions secondary to cardiovascular compromise, and vasculitis. Two woodchucks had neoplastic lesions.

Roth, King, and Tennant: HEPATIC LESIONS IN WOODCHUCKS (MARMOTA MONAX) SERONEGATIVE FOR WOODCHUCK HEPATITIS VIRUS
L. Roth, J. M. King, and B. C. Tennant "HEPATIC LESIONS IN WOODCHUCKS (MARMOTA MONAX) SERONEGATIVE FOR WOODCHUCK HEPATITIS VIRUS," Journal of Wildlife Diseases 27(2), 281-287, (1 April 1991). https://doi.org/10.7589/0090-3558-27.2.281
Received: 11 June 1990; Published: 1 April 1991
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