In May 1991, clinical, pathologic, and virologic investigations were carried out on an 8-yr-old male lion (Panthera leo), with recurrent infections, in captivity with two lionesses in the Zoological Garden of Pistoia, Tuscany, Italy. The lion had severe pneumonia, neutropenia, thrombocytopenia, and' an increase in blood urea nitrogen and creatininemia; in spite of therapy, it died within 3 months. At necropsy, the animal had a lymphoma and other lesions similar to those described in feline immunodeficiency virus-infected cats. We identified FIV gag-sequence using PCR amplification of lymph node tissues.
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1 January 1995
Lentivirus Infection in an African Lion: A Clinical, Pathologic and Virologic Study
Alessandro Poli,
Francesca Abramo,
Paolo Cavicchio,
Patrizia Bandecchi,
Emilia Ghelardi,
Mauro Pistello
Journal of Wildlife Diseases
Vol. 31 • No. 1
January 1995
Vol. 31 • No. 1
January 1995
African lion
case report
FIV-related virus
lentivirus infection
Panthera leo