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1 October 1999 IMMUNIZATION OF DUCKS FOR TYPE C BOTULISM
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Abstract

A single subcutaneous immunization with a vaccine used for protecting ranch mink (Mustela vison) against type C botulism reduced morbidity and mortality in mallard (Anas platyrhynchos) and northern pintail (Anas acuta) ducks challenged with approximately 4.5 × 104 and 2.25 × 104 mouse lethal doses (MLD50), respectively, of botulinum toxin at 10 and 15 days post-immunization (pi). There was no significant protection at 5 days pi. Protection persisted in mallards for 90 days pi. To simulate use of vaccine as a part of treatment of sick birds in the field, mallards were exposed to toxin and, when clinical signs were evident, each bird was treated by intraperitoneal injection of type C botulinum antitoxin and one-half of the birds were immunized. Immunization had no significant effect on recovery from intoxication. At 10 days post-treatment, all birds were challenged with toxin. Clinical signs and mortality were significantly less frequent among immunized birds than among non-immunized birds after the second exposure. Immunization might be useful as part of the treatment regimen in botulism outbreaks.

Martinez and Wobeser: IMMUNIZATION OF DUCKS FOR TYPE C BOTULISM
R. Martinez and G. Wobeser "IMMUNIZATION OF DUCKS FOR TYPE C BOTULISM," Journal of Wildlife Diseases 35(4), 710-715, (1 October 1999). https://doi.org/10.7589/0090-3558-35.4.710
Received: 24 June 1998; Published: 1 October 1999
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