Translator Disclaimer
1 January 2008 Evaluation of the Eastern Cottontail Sylvilagus floridanus as an Amplifying Vertebrate Host for Cache Valley Virus (Bunyaviridae) in Indiana
Author Affiliations +
Abstract

To evaluate the importance of eastern cottontails (Sylvilagus floridanus) as amplifying hosts for Cache Valley virus (CVV), we tested hunter-provided blood samples from northern Indiana for specific neutralizing (N) antibodies against this mosquito-borne bunyavirus. Samples were collected during the winter of 1994–95. Two seronegative eastern cottontails, captured in July 1995, were also infected with CVV by subcutaneous inoculation, and two others were infected by allowing CVV-infected mosquitoes to feed on them. The results indicate that eastern cottontails probably are not important amplifying hosts for CVV. The prevalence of N antibodies against CVV was low (6.0%, n=82) among the hunter-killed animals. Low viremia (<1.8 log10 plaque-forming units/ml) of short duration (1–3 days) were seen in three of four experimentally infected eastern cottontails. The viremias were insufficient for infecting Coquillettidia perturbans, a mosquito species commonly found naturally infected with CVV.

Blackmore and Grimstad: Evaluation of the Eastern Cottontail Sylvilagus floridanus as an Amplifying Vertebrate Host for Cache Valley Virus (Bunyaviridae) in Indiana
Carina G. M. Blackmore and Paul R. Grimstad "Evaluation of the Eastern Cottontail Sylvilagus floridanus as an Amplifying Vertebrate Host for Cache Valley Virus (Bunyaviridae) in Indiana," Journal of Wildlife Diseases 44(1), (1 January 2008). https://doi.org/10.7589/0090-3558-44.1.188
Received: 22 June 2005; Accepted: ; Published: 1 January 2008
JOURNAL ARTICLE
5 PAGES


SHARE
ARTICLE IMPACT
Back to Top