Identified in 1998, Ljungan virus (LV; Picornaviridae) causes type 1 diabetes–like symptoms and myocarditis in bank voles (Myodes glareolus) from Sweden and Denmark, and may be a zoonotic agent of several important diseases (e.g., intrauterine fetal death, type 1 diabetes, Guillain-Barré syndrome, and myocarditis). Using a real-time reverse transcriptase–polymerase chain reaction assay and sequence analysis, we detected LV in bank voles, and for the first time, in yellow-necked mice (Apodemus flavicollis) collected during 2006 from a site in northern Italy. The global distribution of LV and its role as a mammalian pathogen deserve further attention.
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1 January 2010
Ljungan Virus Detected in Bank Voles (Myodes glareolus) and Yellow-Necked Mice (Apodemus flavicollis) from Northern Italy
Heidi C. Hauffe,
Bo Niklasson,
Therese Olsson,
Alessandro Bianchi,
Annapaola Rizzoli,
William Klitz
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Journal of Wildlife Diseases
Vol. 46 • No. 1
January 2010
Vol. 46 • No. 1
January 2010
Apodemus flavicollis
Ljungan virus
Myodes glareolus
Northern Italy
PCR
type 1 diabetes