Equine sarcoid has been diagnosed in endangered Cape mountain zebra (Equus zebra zebra) in at least two game reserves in South Africa, with prevalence as high as 53% in Bontebok National Park. Seven Cape mountain zebras with sarcoids were treated with either surgical excision, 5-fluorouracil, allogenous vaccine, or a combination of 5-fluorouracil and allogenous vaccine. One of the two sarcoids on one of the 5-fluorouracil–treated zebras was left untreated. The microscopic features of the tumors evaluated showed either all or most of the typical epidermal and dermal histologic features of equine sarcoid. The zebras were examined 2 yr posttreatment to determine outcome. All sarcoids had resolved except on the zebra on which one of the sarcoids was left untreated. The efficacy of the three treatment methods in Cape mountain zebra is encouraging.
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1 October 2011
TREATMENT OF EQUINE SARCOID IN SEVEN CAPE MOUNTAIN ZEBRA (EQUUS ZEBRA ZEBRA)
Hendrik J. Marais,
Patrick C. Page
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Journal of Wildlife Diseases
Vol. 47 • No. 4
October 2011
Vol. 47 • No. 4
October 2011
5-fluorouracil
Allogenous vaccine
Cape mountain zebra
sarcoid
surgical excision