The giant panda (Ailuropoda melanoleuca) is known to be susceptible to natural infection with canine distemper virus (CDV). Vaccination of giant pandas with conventional modified live CDV vaccines has been avoided due to the numerous carnivore species known to have become infected with CDV after vaccination. Serum-neutralizing antibodies to CDV were measured after s.c. and i.m. annual vaccination with a canarypox-vectored recombinant CDV vaccine in an adult male and female giant panda over the period of 2 yr. The vaccine proved to be safe, and serum-neutralizing antibody titers interpreted as protective against CDV disease were measured in each animal.
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1 June 2007
SEROLOGIC RESPONSE TO A CANARYPOX-VECTORED CANINE DISTEMPER VIRUS VACCINE IN THE GIANT PANDA (AILUROPODA MELANOLEUCA)
Ellen Bronson,
Sharon L. Deem,
Carlos Sanchez,
Suzan Murray
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Journal of Zoo and Wildlife Medicine
Vol. 38 • No. 2
June 2007
Vol. 38 • No. 2
June 2007
Ailuropoda melanoleuca
Canarypox-vectored recombinant vaccine
canine distemper virus
giant panda
titer
vaccine