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1 January 2010 Chronic Heart Failure due to Severe Endocardiosis in a Gambian Giant Pouched Rat (Cricetomys gambianus)
Kerstin Müller, Britta Horn, Guido Fritsch, Friederike Range, Robert Klopfleisch
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Abstract

A 1.5-yr-old captive male Gambian giant pouched rat (Cricetomys gambianus) died after suffering from anorexia, weakness, and dyspnea for 3 wk. Thoracic radiographs of thorax and abdomen and computed tomography showed a severe biventricular enlargement of the heart and a moderate hepatomegaly. Necropsy revealed a severe, bilateral hypertrophic cardiomyopathy and dilation of the right ventricle due to multifocal bilateral, valvular endocardiosis of all atrioventricular valves and acute hepatic congestion. Histologically, the atrioventricular valves were multifocally thickened by a marked endocardiosis with stromal accumulation of Periodic acid-Schiff (PAS)-positive, mucinous material. Although common in dogs, endocardiosis has not been described in Nesomyidaes. As in other affected species, the pathogenesis of endocardiosis in this species remains unclear.

Kerstin Müller, Britta Horn, Guido Fritsch, Friederike Range, and Robert Klopfleisch "Chronic Heart Failure due to Severe Endocardiosis in a Gambian Giant Pouched Rat (Cricetomys gambianus)," Journal of Zoo and Wildlife Medicine 41(1), 137-139, (1 January 2010). https://doi.org/10.1638/2008-0131.1
Received: 3 August 2008; Published: 1 January 2010
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