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1 September 2011 Minimum Anesthetic Concentration and Cardiovascular Dose–Response Relationship of Isoflurane in Cinereous Vultures (Aegypius monachus)
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Abstract

This study aimed to determine the minimum anesthetic concentration (MAC) and dose-related cardiovascular effects of isoflurane during controlled ventilation in cinereous vultures (Aegypius monachus). The MAC was determined for 10 cinereous vultures as the midpoint between the end-tidal isoflurane concentration that allows gross purposeful movement and that which prevents the movement in response to clamping a pedal digit. Immediately after the MAC was determined, the cardiovascular effects of isoflurane at 1.0, 1.5, and 2.0 times the MAC were investigated in seven of the 10 birds. The MAC of isoflurane for 10 cinereous vultures during controlled ventilation was 1.06 ± 0.07% (mean ± SD). When the isoflurane concentration was increased to 1.5 and 2.0 times the MAC, there was significant dose-dependent decrease in the arterial blood pressure. However, the heart rate did not change over a range of 1.0 to 2.0 times the MAC.

American Association of Zoo Veterinarians
Young K Kim, Scott S Lee, Euy H Suh, Lyon Lee, Hee C Lee, Hyo J Lee, and Seong C Yeon "Minimum Anesthetic Concentration and Cardiovascular Dose–Response Relationship of Isoflurane in Cinereous Vultures (Aegypius monachus)," Journal of Zoo and Wildlife Medicine 42(3), 499-503, (1 September 2011). https://doi.org/10.1638/2010-0151.1
Received: 4 October 2010; Published: 1 September 2011
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