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14 December 2012 MEDIUM-GRADE ASTROCYTOMA IN A COUGAR (PUMA CONCOLOR)
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Abstract

A 17-year-old, male castrated cougar (Puma concolor) was presented minimally responsive and severely depressed, with bilateral mydriasis and absent pupillary light response. On gross examination of the brain, there was a tan-to-gray, invasive mass with a central cavitation on the ventral aspect in the left cerebral hemisphere, rostral to the caudate nucleus. On histopathologic examination, the mass was composed of sheets of medium-sized, round-to-polygonal cells that were multifocally separated by islands of neuropil. Approximately 80% of the neoplastic cells showed strong cytoplasmic labeling for glial fibrillary acidic protein. These findings were consistent with a medium-grade astrocytoma. To the authors' knowledge, neoplastic disease of the central nervous system has not been previously reported in cougars.

American Association of Zoo Veterinarians
Hirotaka Kondo, Angelique M. Leone, Claire Erlacher-Reid, Joy Gary, Matti Kiupel, Lisa L. Farina, and Jeffrey R. Abbott "MEDIUM-GRADE ASTROCYTOMA IN A COUGAR (PUMA CONCOLOR)," Journal of Zoo and Wildlife Medicine 43(4), 956-960, (14 December 2012). https://doi.org/10.1638/2012-0106R1.1
Received: 21 April 2012; Published: 14 December 2012
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