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1 September 2015 MANAGEMENT OF ACUTE RENAL FAILURE WITH DELAYED HYPERCALCEMIA SECONDARY TO SARCOCYSTIS NEURONA–INDUCED MYOSITIS AND RHABDOMYOLYSIS IN A CALIFORNIA SEA LION (ZALOPHUS CALIFORNIANUS)
Amy B. Alexander, Christopher S. Hanley, Mary C. Duncan, Kyle Ulmer, Luis R. Padilla
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Abstract

A 3-yr-old captive-born California sea lion (Zalophus californianus) developed Sarcocystis neurona–induced myositis and rhabdomyolysis that led to acute renal failure. The sea lion was successfully managed with fluid therapy, antiprotozoals, antibiotics, anti-inflammatories, antiemetics, gastroprotectants, and diuretics, but developed severe delayed hypercalcemia, a syndrome identified in humans after traumatic or exertion-induced rhabdomyolysis. Treatment with calcitonin was added to the management, and the individual recovered fully. The case emphasizes that animals with rhabdomyolysis-induced renal failure risk developing delayed hypercalcemia, which may be life threatening, and calcium levels should be closely monitored past the resolution of renal failure.

Copyright 2015 by American Association of Zoo Veterinarians
Amy B. Alexander, Christopher S. Hanley, Mary C. Duncan, Kyle Ulmer, and Luis R. Padilla "MANAGEMENT OF ACUTE RENAL FAILURE WITH DELAYED HYPERCALCEMIA SECONDARY TO SARCOCYSTIS NEURONA–INDUCED MYOSITIS AND RHABDOMYOLYSIS IN A CALIFORNIA SEA LION (ZALOPHUS CALIFORNIANUS)," Journal of Zoo and Wildlife Medicine 46(3), 652-656, (1 September 2015). https://doi.org/10.1638/2015-0075.1
Received: 2 April 2015; Published: 1 September 2015
JOURNAL ARTICLE
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KEYWORDS
California sea lion
hypercalcemia
myositis
renal failure
Sarcocystis neurona
Zalophus californianus
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