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17 March 2020 USE OF CLINDAMYCIN IN PALLAS' CATS [OTOCOLOBUS (FELIS) MANUL] TO REDUCE JUVENILE TOXOPLASMOSIS-ASSOCIATED MORTALITY RATES
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Abstract

Pallas' cat [Otocolobus (Felis) manul] experiences a high mortality rate from toxoplasmosis. During the period 2006–2016, the overall mortality rate for this species from all causes during the first year of life was 71.59% in European Association of Zoos and Aquaria institutions, with the most significant infectious cause from systemic toxoplasmosis (20.6%) as confirmed by postmortem examination and histopathology. Clindamycin was used starting in 2014 in two collections that had previously experienced 100% mortality rates by toxoplasmosis in kittens less than one year of age, covering key Toxoplasma gondii exposure periods for kittens (n = 17) as a prophylactic measure. This protocol resulted in a 67.03% (95% confidence interval 41.76–78.61%) reduction in the first year mortality rate over a two-year period to 5.88% in those animals treated.

Copyright 2020 by American Association of Zoo Veterinarians
Simon J. Girling, Romain Pizzi, Adam D. Naylor, Douglas Richardson, Una Richardson, Jane Harley, Georgina Cole, Donna Brown, Mary Fraser, Emma Tillman, and David Barclay "USE OF CLINDAMYCIN IN PALLAS' CATS [OTOCOLOBUS (FELIS) MANUL] TO REDUCE JUVENILE TOXOPLASMOSIS-ASSOCIATED MORTALITY RATES," Journal of Zoo and Wildlife Medicine 51(1), 39-45, (17 March 2020). https://doi.org/10.1638/2018-0206
Accepted: 25 October 2019; Published: 17 March 2020
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