Ixodes scapularis (Blacklegged Tick), vector of Lyme disease, has a broad distribution in eastern North America, but is relatively rare in Missouri. In this study, we report the change in abundance of this species in Adair County, MO, from 2006 to 2015. We collected data from 85 small-mammal trapping sessions beginning in 2006, and from 175 off-host sampling sessions using both drag and bait sampling beginning in 2007. The total number of Blacklegged Ticks collected in this study was 182; we collected <10 Blacklegged Ticks in most years. However, we collected 61.5% of specimens in 2014 and 86% in the last 3 years. Systematic, long-term monitoring has provided information about the dynamics of a tick species with low abundance.