This is the fifth installment of a treatment of Ocotea Aubl. occurring above 1000-m altitude in the Andean countries of Venezuela, Colombia, Ecuador, Peru, and Bolivia. This part covers species with unisexual flowers lacking distinctive characters such as presence of domatia or erect or dense pubescence on leaves. Twenty-six species are treated, of which 12 are new to science. These are O. nidiae van der Werff from Venezuela; O. erugata van der Werff, O. gymnantha van der Werff, and O. lorda van der Werff from Colombia; O. ceronii van der Werff, O. depilis van der Werff, O. homeieri van der Werff, and O. pilosa van der Werff from Ecuador; and O. calcicola van der Werff, O. fulgida van der Werff, O. nana van der Werff, and O. tunquiensis van der Werff from Peru. Ocotea cernua (Nees) Mez is synonymized with O. leptobotra (Ruiz & Pav.) Mez and O. longifolia Kunth is synonymized with O. aurantiodora (Ruiz & Pav.) Mez.