U.S. states are often the primary decision makers during a public health crisis. The COVID-19 pandemic led to several different reopening processes across states based on their unique characteristics. We analyze whether states' reopening policy decisions were driven by their public health preparedness, resources, COVID-19 impact, or state politics and political culture. To do so, we summarized state characteristics and compared them across three categories of reopening scores in a bivariate analysis using the chi-square or Fisher exact test for the categorical variables and a one-way analysis of variance (ANOVA) for the continuous variables. A cumulative logit model was used to assess the primary research question. A significant factor in a state's reopening decision was the party of the governor, regardless of the party in control of the legislature, state political culture, public health preparedness, cumulative number of deaths per 100,000, and Opportunity Index score.