Heteroplea is a Neotropical genus of Pleidae that is easily separated from other members of the family by having a distinct raised callus on the dorsal posterior of the head and sharing a 3,3,3 tarsal formula with the Palearctic genus Plea. Heteroplea acanthoscelis, n. sp. is described and can be differentiated from all other species of Pleidae in having raptorial spines on its prothoracic tibia, with smaller, similar spines on the mesothoracic tibia. With this description, H. acanthoscelis n. sp. becomes the second member of this genus; both species are currently known only from Venezuela.