Four species in four separate genera of Tineidae (Lepidoptera) are described from bat caves located in Kenya and South Africa. These include Tinea suswaensis, new species (Kenya), Phereoeca coprophaga, new species (South Africa), Monopis truncata, new species (South Africa), and Setomorpha rutella Zeller (South Africa). All species were collected on or near bat guano deposits in either the twilight or dark zones of the caves. Occasionally the moths were found resting on the walls of the cave near the guano deposits. Descriptions for each species, including the larval stage if known, are provided.