This paper considers the dose–effect relationship for unstable chromosome aberration yields in human lymphocytes in very low-dose range. Data are presented for 60Co γ-ray doses of 0, 10, 20, 40 and 1000 mGy. More than 5,000 metaphases were scored for each data point at the very low doses, and each cell was double-checked using a semi-automated metaphase finding/relocation system. Aberration yields of dicentrics plus centric rings followed an excellent linear dose response down to zero dose; the yields were significantly above the control frequency from 20 mGy.
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4 November 2010
The Dose Response of Chromosome Aberrations in Human Lymphocytes Induced In Vitro by Very Low-Dose γ Rays
Toshiyasu Iwasaki,
Yoshio Takashima,
Toshikazu Suzuki,
Mitsuaki A. Yoshida,
Isamu Hayata
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Radiation Research
Vol. 175 • No. 2
February 2011
Vol. 175 • No. 2
February 2011