BioOne.org will be down briefly for maintenance on 12 February 2025 between 18:00-21:00 Pacific Time US. We apologize for any inconvenience.
How to translate text using browser tools
18 July 2024 A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure
Mark P. Little, Dimitry Bazyka, Amy Berrington de Gonzalez, Alina V. Brenner, Vadim V. Chumak, Harry M. Cullings, Robert D. Daniels, Benjamin French, Eric Grant, Nobuyuki Hamada, Michael Hauptmann, Gerald M. Kendall, Dominique Laurier, Choonsik Lee, Won Jin Lee, Martha S. Linet, Kiyohiko Mabuchi, Lindsay M. Morton, Colin R. Muirhead, Dale L. Preston, Preetha Rajaraman, David B. Richardson, Ritsu Sakata, Jonathan M. Samet, Steven L. Simon, Hiromi Sugiyama, Richard Wakeford, Lydia B. Zablotska
Author Affiliations +
Abstract

In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods of exposure assessment and dose estimation along with brief consideration of sources of bias for a few of the more important studies. We examine the findings from the epidemiological studies of the Japanese atomic bomb survivors, persons exposed to radiation for diagnostic or therapeutic purposes, those exposed to environmental sources including Chornobyl and other reactor accidents, and occupationally exposed cohorts. We also summarize results of pooled studies. These summaries are necessarily brief, but we provide references to more detailed information. We discuss possible future directions of study, to include assessment of susceptible populations, and possible new populations, data sources, study designs and methods of analysis.

Mark P. Little, Dimitry Bazyka, Amy Berrington de Gonzalez, Alina V. Brenner, Vadim V. Chumak, Harry M. Cullings, Robert D. Daniels, Benjamin French, Eric Grant, Nobuyuki Hamada, Michael Hauptmann, Gerald M. Kendall, Dominique Laurier, Choonsik Lee, Won Jin Lee, Martha S. Linet, Kiyohiko Mabuchi, Lindsay M. Morton, Colin R. Muirhead, Dale L. Preston, Preetha Rajaraman, David B. Richardson, Ritsu Sakata, Jonathan M. Samet, Steven L. Simon, Hiromi Sugiyama, Richard Wakeford, and Lydia B. Zablotska "A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure," Radiation Research 202(2), 432-487, (18 July 2024). https://doi.org/10.1667/RADE-24-00021.1
Received: 16 January 2024; Accepted: 23 April 2024; Published: 18 July 2024
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top