Sustained reproduction is critical for successful restoration of extirpated populations. Evaluating success of restoration efforts requires an understanding of reproductive capacity in such populations. We examined age-specific reproductive capacity of a Lontra canadensis (River Otter) population in southern Missouri that was the focus of intense restoration efforts in the 1980s and early 1990s. We collected carcasses of 387 legally harvested female Otters from 1996–1999. Otters ranged in age from 1–11 years, with juveniles (<1 yr) the dominant (41.1%) age class. Mean annual corpora lutea counts were high ( = 2.48 ± 0.12) and present in 72.8% of adult (>1 yr) Otters. Our results indicate that the southern Missouri River Otter population has one of the greatest recorded potential reproductive capacities for that species.