Mortality and growth inhibition effect of Trichiliahavanensis, Annona cherimola, and Carica papaya seed powders were evaluated on Scyphophorus acupunctatus Gyll. (Coleoptera: Curculionidae). Seeds of T. havanensis and C. papayaat 15% were very toxic to S. acupunctatus, causing 100 and 90% larval mortality. Seed powder of A. cherimola killed 63% of the weevils. All powders inhibited the weight of the insect. Annona cherimola was the most effective, decreasing the weight of larvae, pupae, and adults 98.5, 40.6, and 45.0%. These results show that T. havanensis, C. papaya, and A. cherimola seed powders have the potential to control the S. acupunctatus weevil.